DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors

Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins. Here we examine whether DAZL directly regulates progenitor spermatogonia using a conditional genetic mouse model and in vivo biochemical approaches combined with chemical synchronization of spermatogenesis. W...

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Pubblicato in:eLife
Autori principali: Mikedis, Maria M, Fan, Yuting, Nicholls, Peter K, Endo, Tsutomu, Jackson, Emily K, Cobb, Sarah A, de Rooij, Dirk G, Page, David C
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2020
Soggetti:
Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7445011/
https://ncbi.nlm.nih.gov/pubmed/32686646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.56523
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