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MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation

Proteus mirabilis, a Gram-negative uropathogen, is a major causative agent in catheter-associated urinary tract infections (CAUTI). Mannose-resistant Proteus-like fimbriae (MR/P) are crucially important for P. mirabilis infectivity and are required for biofilm formation and auto-aggregation, as well...

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Détails bibliographiques
Publié dans:PLoS Pathog
Auteurs principaux: Jiang, Wangshu, Ubhayasekera, Wimal, Breed, Michael C., Norsworthy, Allison N., Serr, Nina, Mobley, Harry L. T., Pearson, Melanie M., Knight, Stefan D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444556/
https://ncbi.nlm.nih.gov/pubmed/32780778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008707
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