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Disruption of fibronectin fibrillogenesis affects intraocular pressure (IOP) in BALB/cJ mice

Increased deposition of fibronectin fibrils containing EDA+fibronectin by TGFβ2 is thought to be involved in the reduction of aqueous humor outflow across the trabecular meshwork (TM) of the eye and the elevation in intraocular pressure (IOP) observed in primary open angle glaucoma (POAG). Using a f...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Faralli, Jennifer A., Filla, Mark S., McDowell, Colleen M., Peters, Donna M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444551/
https://ncbi.nlm.nih.gov/pubmed/32822410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237932
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