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Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway

Oxidative stress induces excessive apoptosis resulting in the reduction of intervertebral disc cells, the consequent reduction of extracellular matrix (ECM) synthesis, and compositional changes, which is the pathological basis for intervertebral disc degeneration (IVDD). The present study explored t...

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Publicado en:Exp Ther Med
Autor principal: Liu, Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444416/
https://ncbi.nlm.nih.gov/pubmed/32855694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.9052
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