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Unraveling the molecular heterogeneity in type 2 diabetes: a potential subtype discovery followed by metabolic modeling

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a complex multifactorial disease with a high prevalence worldwide. Insulin resistance and impaired insulin secretion are the two major abnormalities in the pathogenesis of T2DM. Skeletal muscle is responsible for over 75% of the glucose uptake and plays...

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Bibliografske podrobnosti
izdano v:BMC Med Genomics
Main Authors: Khoshnejat, Maryam, Kavousi, Kaveh, Banaei-Moghaddam, Ali Mohammad, Moosavi-Movahedi, Ali Akbar
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444195/
https://ncbi.nlm.nih.gov/pubmed/32831068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00767-0
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