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HLA-associated protection of lymphocytes during influenza virus infection

BACKGROUND: Heterozygosity at HLA class I loci is generally considered beneficial for host defense. We report here an element of HLA class I homozygosity that may or may not help preserve its existence in populations but which could indicate a new avenue for antiviral research. METHODS: Lymphocytes...

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Bibliographic Details
Published in:Virol J
Main Authors: Ochoa, Eliana E., Huda, Ruksana, Scheibel, Steven F., Nichols, Joan E., Mock, David J., El-Daher, Nayef, Domurat, Frank M., Roberts, Norbert J.
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444183/
https://ncbi.nlm.nih.gov/pubmed/32831108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-020-01406-x
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