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Loss of PTEN expression is associated with PI3K pathway-dependent metabolic reprogramming in hepatocellular carcinoma

BACKGROUND: Metabolic reprogramming, in which energetic metabolism changes from oxidative phosphorylation to glycolysis, is well-accepted as a hallmark of cancers including hepatocellular carcinoma (HCC). A growing body of evidence suggests the involvement of oncogenes and tumor suppressor genes in...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Zhao, Chuanzong, Wang, Ben, Liu, Enyu, Zhang, Zongli
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444061/
https://ncbi.nlm.nih.gov/pubmed/32831114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00622-w
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