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Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles

Immunotherapy is emerging as one of the most effective methods for treating many cancers. However, immunotherapy can still introduce significant off-target toxicity, and methods are sought to enable targeted immunotherapy at tumor sites. Here, we show that relatively large (>100-nm) anionic nanop...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Haber, Tom, Cornejo, Yvonne R., Aramburo, Soraya, Flores, Linda, Cao, Pengpeng, Liu, Alice, Mooney, Rachael, Gilchrist, Megan, Tirughana, Revathiswari, Nwokafor, Ugochi, Abidi, Wafa, Han, Ernest, Dellinger, Thanh, Wakabayashi, Mark T., Aboody, Karen S., Berlin, Jacob M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443897/
https://ncbi.nlm.nih.gov/pubmed/32732430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917424117
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