Innate immune response in neuronopathic forms of Gaucher disease confers resistance against viral-induced encephalitis

Both monogenic diseases and viral infections can manifest in a broad spectrum of clinical phenotypes that range from asymptomatic to lethal, suggesting that other factors modulate disease severity. Here, we examine the interplay between the genetic neuronopathic Gaucher’s disease (nGD), and neuroinv...

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Vydáno v:Acta Neuropathol Commun
Hlavní autoři: Melamed, Sharon, Avraham, Roy, Rothbard, Deborah E., Erez, Noam, Israely, Tomer, Klausner, Ziv, Futerman, Anthony H., Paran, Nir, Vitner, Einat B.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443817/
https://ncbi.nlm.nih.gov/pubmed/32831144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01020-6
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