A whole-genome screen identifies Salmonella enterica serovar Typhi genes involved in fluoroquinolone susceptibility

OBJECTIVES: A whole-genome screen at sub-gene resolution was performed to identify candidate loci that contribute to enhanced or diminished ciprofloxacin susceptibility in Salmonella enterica serovar Typhi. METHODS: A pool of over 1 million transposon insertion mutants of an S. Typhi Ty2 derivative...

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Dettagli Bibliografici
Pubblicato in:J Antimicrob Chemother
Autori principali: Turner, A Keith, Eckert, Sabine E, Turner, Daniel J, Yasir, Muhammud, Webber, Mark A, Charles, Ian G, Parkhill, Julian, Wain, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443733/
https://ncbi.nlm.nih.gov/pubmed/32514543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkaa204
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