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Structural features of bovine colostral immunoglobulin that confer proteolytic stability in a simulated intestinal fluid

Bovine colostral antibodies, purified from cow's milk produced immediately after calving, have enhanced resistance to degradation by intestinal proteases relative to antibodies from human or bovine serum, making them of particular interest as orally administered therapeutic agents. However, the...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Burton, Randall E., Kim, Skaison, Patel, Rutvij, Hartman, Deborah S., Tracey, Daniel E., Fox, Barbara S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443484/
https://ncbi.nlm.nih.gov/pubmed/32665404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014327
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