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Simplified detection of polyhistidine-tagged proteins in gels and membranes using a UV-excitable dye and a multiple chelator head pair

The polyhistidine tag (His-tag) is one of the most popular protein tags used in the life sciences. Traditionally, the detection of His-tagged proteins relies on immunoblotting with anti-His antibodies. This approach is laborious for certain applications, such as protein purification, where time and...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Raducanu, Vlad-Stefan, Isaioglou, Ioannis, Raducanu, Daniela-Violeta, Merzaban, Jasmeen S., Hamdan, Samir M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443479/
https://ncbi.nlm.nih.gov/pubmed/32647010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014132
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