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Heterologous expression of concatenated nicotinic ACh receptors: Pros and cons of subunit concatenation and recommendations for construct designs

BACKGROUND AND PURPOSE: Concatenation of Cys‐loop receptor subunits is a commonly used technique to ensure experimental control of receptor assembly. However, we recently demonstrated that widely used constructs did not lead to the expression of uniform pools of ternary and more complex receptors. T...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Liao, Vivian Wan Yu, Kusay, Ali Saad, Balle, Thomas, Ahring, Philip Kiær
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443467/
https://ncbi.nlm.nih.gov/pubmed/32627170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15188
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