Cinnamaldehyde Treatment of Prostate Cancer-Associated Fibroblasts Prevents Their Inhibitory Effect on T Cells Through Toll-Like Receptor 4

INTRODUCTION: Cancer-associated fibroblasts (CAFs) promote tumor progression; thus, drugs that can modify CAFs need to be identified. METHODS: To test the effect of cinnamaldehyde on prostate CAFs, the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl-2H-tetrazolium bromide assay was used to determine their...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Mei, Jie, Ma, Jing, Xu, Yuwei, Wang, Yuanyuan, Hu, Minghua, Ma, Fangli, Qin, Zhihai, Xue, Rui, Tao, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443443/
https://ncbi.nlm.nih.gov/pubmed/32884240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S241410
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