Combination of thermally ablative focused ultrasound with gemcitabine controls breast cancer via adaptive immunity

BACKGROUND: Triple-negative breast cancer (TNBC) remains recalcitrant to most targeted therapy approaches. However, recent clinical studies suggest that inducing tumor damage can render TNBC responsive to immunotherapy. We therefore tested a strategy for immune sensitization of murine TNBC (4T1 tumo...

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Bibliographic Details
Published in:J Immunother Cancer
Main Authors: Sheybani, Natasha D, Witter, Alexandra R, Thim, Eric A, Yagita, Hideo, Bullock, Timothy N J, Price, Richard J
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2020
Subjects:
Clinical/Translational Cancer Immunotherapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443308/
https://ncbi.nlm.nih.gov/pubmed/32819975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001008
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