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The Development and Application of a Base Editor in Biomedicine

Using a base editor to generate monogenic disease models and correct pathogenic point mutations is a breakthrough technology for exploration and treatment of human diseases. As a burgeoning approach for genomic modification, the fused CRISPR/Cas9 with various deaminase separately has significantly i...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Wang, Fang, Zeng, Yuqiang, Wang, Yi, Niu, Yuyu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443245/
https://ncbi.nlm.nih.gov/pubmed/32855962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/2907623
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