Beneficial Effect of Genistein on Diabetes-Induced Brain Damage in the ob/ob Mouse Model

PURPOSE: Diabetes mellitus (DM)-induced brain damage is characterized by cellular, molecular and functional changes. The mechanisms include oxidative stress, neuroinflammation, reduction of neurotrophic factors, insulin resistance, excessive amyloid beta (Aβ) deposition and Tau phosphorylation. Both...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Li, Rong-zi, Ding, Xiao-Wen, Geetha, Thangiah, Al-Nakkash, Layla, Broderick, Tom L, Babu, Jeganathan Ramesh
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7443039/
https://ncbi.nlm.nih.gov/pubmed/32884237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S249608
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