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GRP78 targeting: Hitting two birds with a stone

BACKGROUND: Glucose regulating protein 78 (GRP78) is one member of the Heat Shock Protein family of chaperone proteins (HSPA5) found in eukaryotes. It acts as the master of the Unfolded Protein Response (UPR) process in the lumen of the Endoplasmic Reticulum (ER). SCOPE: Under the stress of unfolded...

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Publicado en:Life Sci
Main Authors: Elfiky, Abdo A., Baghdady, Ahmed M., Ali, Shehab A., Ahmed, Marwan I.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442953/
https://ncbi.nlm.nih.gov/pubmed/32841659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2020.118317
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