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TGF-β is insufficient to induce adipocyte state loss without concurrent PPARγ downregulation
Cell plasticity, the ability of differentiated cells to convert into other cell types, underlies the pathogenesis of many diseases including the transdifferentiation of adipocytes (fat cells) into myofibroblasts in the pathogenesis of dermal fibrosis. Loss of adipocyte identity is an early step in d...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442643/ https://ncbi.nlm.nih.gov/pubmed/32826933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71100-z |
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