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Loss of endothelin type B receptor function improves insulin sensitivity in rats

High salt intake (HS) is associated with obesity and insulin resistance. ET-1, a peptide released in response to HS, inhibits the actions of insulin on cultured adipocytes through ET-1 type B (ETB) receptors; however, the in vivo implications of ETB receptor activation on lipid metabolism and insuli...

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Publicado en:Can J Physiol Pharmacol
Main Authors: Gonzalez, Osvaldo Rivera, Kasztan, Malgorzata, Johnston, Jermaine G., Hyndman, Kelly A., Speed, Joshua S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442597/
https://ncbi.nlm.nih.gov/pubmed/32083942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjpp-2019-0666
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