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Differential Regulation of TREM2 and CSF1R in CNS Macrophages in an SIV/Macaque Model of HIV CNS Disease

HIV-associated neuroinflammation is primarily driven by CNS macrophages including microglia. Regulation of these immune responses, however, remains to be characterized in detail. Using the SIV/macaque model of HIV, we evaluated CNS expression of Triggering Receptor Expressed on Myeloid cells 2 (TREM...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Knight, Audrey C., Brill, Samuel A., Solis, Clarisse V., Richardson, Morgan R., McCarron, Megan E., Queen, Suzanne E., Bailey, Charles C., Mankowski, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442592/
https://ncbi.nlm.nih.gov/pubmed/32488843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-020-00844-1
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