Phase 3 Trial of a Small-volume Subcutaneous 6-Month Duration Leuprolide Acetate Treatment for Central Precocious Puberty

CONTEXT: Gonadotropin-releasing hormone agonists (GnRHas) are standard of care for central precocious puberty (CPP). A 6-month subcutaneous injection has recently been approved by the Food and Drug Administration. OBJECTIVE: Determine efficacy, pharmacokinetics, and safety of 6-month 45-mg subcutane...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Klein, Karen O, Freire, Analía, Gryngarten, Mirta Graciela, Kletter, Gad B, Benson, Matthew, Miller, Bradley S, Dajani, Tala S, Eugster, Erica A, Mauras, Nelly
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Online Only Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442270/
https://ncbi.nlm.nih.gov/pubmed/32738042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa479
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