Hippo/MST blocks breast cancer by downregulating WBP2 oncogene expression via miRNA processor Dicer

WBP2 transcription coactivator is an emerging oncoprotein and a key node of convergence between EGF and Wnt signaling pathways. Understanding how WBP2 is regulated has important implications for cancer therapy. WBP2 is tightly controlled by post-translational modifications, including phosphorylation...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Lim, Shen Kiat, Tabatabaeian, Hossein, Lu, Ssu Yi, Kang, Shin-Ae, Sundaram, Gopinath Meenakshi, Sampath, Prabha, Chan, Siew Wee, Hong, Wan Jin, Lim, Yoon Pin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441404/
https://ncbi.nlm.nih.gov/pubmed/32820148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02901-3
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