The different role of YKL-40 in glioblastoma is a function of MGMT promoter methylation status

Inter- and intratumoral heterogeneity is a hallmark of glioblastoma (GBM) that facilitates recurrence, treatment resistance, and worse prognosis. O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation is a significant prognostic marker for Temozolomide (TMZ) resistance in GBM patients....

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Dades bibliogràfiques
Publicat a:Cell Death Dis
Autors principals: Chen, Wei-jun, Zhang, Xiang, Han, Hua, Lv, Jian-nan, Kang, En-ming, Zhang, Yu-lian, Liu, Wei-ping, He, Xiao-sheng, Wang, James, Wang, Gui-huai, Yu, Yan-bing, Zhang, Wei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441403/
https://ncbi.nlm.nih.gov/pubmed/32820151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02909-9
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