CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10

PURPOSE: Ciliary neurotrophic factor (CNTF) is a well-characterized neurotrophic factor currently in clinical trials for the treatment of macular telangiectasia type II. Our previous work showed that CNTF-induced STAT3 signaling is a potent inhibitor of pathologic preretinal neovascular tuft formati...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Bucher, Felicitas, Aguilar, Edith, Marra, Kyle V., Rapp, Julian, Arnold, Jakob, Diaz-Aguilar, Sophia, Lange, Clemens, Agostini, Hansjürgen, Schlunck, Günther, Stahl, Andreas, Friedlander, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2020
Témata:
Retinal Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441336/
https://ncbi.nlm.nih.gov/pubmed/32780864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.20
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