BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study

BACKGROUND: An association between BRCA pathogenic variants and an increased endometrial cancer risk, specifically serous-like endometrial cancer, has been postulated but remains unproven, particularly for BRCA2 carriers. Mechanistic evidence is lacking, and any link may be related to tamoxifen expo...

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Pubblicato in:Eur J Cancer
Autori principali: Kitson, Sarah J., Bafligil, Cemsel, Ryan, Neil A.J., Lalloo, Fiona, Woodward, Emma R., Clayton, Richard D., Edmondson, Richard J., Bolton, James, Crosbie, Emma J., Evans, D. Gareth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier Science Ltd 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441309/
https://ncbi.nlm.nih.gov/pubmed/32698099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2020.05.030
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