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Gradual Increase in Environmental Light Intensity Induces Oxidative Stress and Inflammation and Accelerates Retinal Neurodegeneration

PURPOSE: Retinitis pigmentosa (RP) is a blinding neurodegenerative disease of the retina that can be affected by many factors. The present study aimed to analyze the effect of different environmental light intensities in rd10 mice retina. METHODS: C57BL/6J and rd10 mice were bred and housed under th...

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Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Kutsyr, Oksana, Sánchez-Sáez, Xavier, Martínez-Gil, Natalia, de Juan, Emilio, Lax, Pedro, Maneu, Victoria, Cuenca, Nicolás
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7441298/
https://ncbi.nlm.nih.gov/pubmed/32744596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.10.1
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