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The Parameter-Fitness Landscape of lexA Autoregulation in Escherichia coli

Feedback mechanisms are fundamental to the control of physiological responses. One important example in gene regulation, termed negative autoregulation (NAR), occurs when a transcription factor (TF) inhibits its own production through transcriptional repression. This enables more-rapid homeostatic c...

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Publicat a:mSphere
Autors principals: Kozuch, Beverley C., Shaffer, Marla G., Culyba, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440846/
https://ncbi.nlm.nih.gov/pubmed/32817380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00718-20
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