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Protein A-Mediated Binding of Staphylococcus spp. to Antibodies in Flow Cytometric Assays and Reduction of This Binding by Using Fc Receptor Blocking Reagent

Staphylococcus aureus and other coagulase-positive Staphylococcus spp. bind the Fc region of IgG antibodies through expression of protein A (SpA). These species have consequently been a source of false-positive signals in antibody-based assays designed to detect other target bacteria. Here, flow cyt...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: Cronin, Ultan P., Girardeaux, Laura, O’Meara, Elaine, Wilkinson, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440785/
https://ncbi.nlm.nih.gov/pubmed/32591386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01435-20
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