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Genome Topology Control of Antigen Receptor Gene Assembly

The past decade has increased our understanding of how genome topology controls RAG endonuclease-mediated assembly of lymphocyte Ag receptor genes. New technologies have illuminated how the large IgH, Igκ, TCRα/δ, and TCRβ loci fold into compact structures that place their numerous V gene segments i...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Allyn, Brittney M., Lee, Kyutae D., Bassing, Craig H.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440635/
https://ncbi.nlm.nih.gov/pubmed/32366683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901356
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