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Germline Mutations in DNA Repair Genes in Patients With Metastatic Castration-resistant Prostate Cancer

Background/Aim: The aim of this study was to analyse the genetic profiles of metastatic castration-resistant prostate cancer (mCRPC) by using next generation sequencing to identify variants with pathogenic potential in nine DNA repair genes – BRCA1, BRCA2, RAD50, RAD51, RAD51C/D, ATM and ATR. Materi...

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Bibliografske podrobnosti
izdano v:In Vivo
Main Authors: HOLECKOVA, KLAUDIA, BALUCHOVA, KATARINA, HIVES, MARK, MUSAK, LUDOVIT, KLIMENT SR, JAN, SKERENOVA, MARIA
Format: Artigo
Jezik:Inglês
Izdano: International Institute of Anticancer Research 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439863/
https://ncbi.nlm.nih.gov/pubmed/32606146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.11971
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