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Quantification of residual AEBSF-related impurities by reversed-phase liquid chromatography()
During research of a broadly neutralizing antibody (bNAb) for HIV-1 infection, site-specific clipping was observed during cell culture incubation. Protease inhibitor, 4-(2-aminoethyl) benzenesulfonyl fluoride (AEBSF), was supplemented to the cell culture feeding to mitigate clipping as one of the co...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Chromatogr B Analyt Technol Biomed Life Sci |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7439605/ https://ncbi.nlm.nih.gov/pubmed/30953918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2019.03.022 |
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