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A homozygous missense mutation of WFS1 gene causes Wolfram's syndrome without hearing loss in an Iranian family (a report of clinical heterogeneity)

BACKGROUND: Wolfram's syndrome (WFS) is a hereditary (autosomal recessive) neurodegenerative disorder. The clinical features are related to diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD) with other variable clinical manifestations. Pathogenic variants in the WFS1 g...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Lab Anal
Päätekijät: Torkamandi, Shahram, Rezaei, Somaye, Mirfakhraie, Reza, Bayat, Sahar, Piltan, Samira, Gholami, Milad
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439424/
https://ncbi.nlm.nih.gov/pubmed/32419160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23358
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