Significant association between DHFR promoter methylation and ischemic stroke in a Chinese hypertensive population

OBJECTIVE: DHFR encodes dihydrofolate reductase, a major enzyme in the metabolism of folate, and is a candidate gene for ischemic stroke (IS). Therefore, we aimed to investigate the association between DHFR promoter methylation and IS in a Chinese population with primary hypertension. METHODS: Quant...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Hu, Jingcen, Zhu, Hong, Xu, Guodong, Chen, Zhu, Li, Lian, Wang, Shuyu, Deng, Hongxia, Bao, Xiaoming, Shen, Zhisen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439332/
https://ncbi.nlm.nih.gov/pubmed/32319147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.23322
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