Mature vascular smooth muscle cells, but not endothelial cells, serve as the major cellular source of intimal hyperplasia in vein grafts

OBJECTIVE: Neointima (NI) formation is a primary cause of intermediate to late vein graft (VG) failure. However, the precise source of NI cells in VGs remains unclear. APPROACH AND RESULTS: Herein we clarify the relative contributions of mature vascular smooth muscle cells (SMCs) and endothelial cel...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Wu, Weiwei, Wang, Chunyan, Zang, Huimei, Qi, Lei, Azhar, Mohamad, Nagarkatti, Mitzi, Nagarkatti, Prakash, Cai, Guoshuai, Weiser-Evans, Mary C.M., Cui, Taixing
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7439253/
https://ncbi.nlm.nih.gov/pubmed/32493169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.314465
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