CAR T-Cell Therapy Is Effective but Not Long-Lasting in B-Cell Lymphoma of the Brain

Advanced central nervous system (CNS) lymphoma is an exclusion criterion for most chimeric antigen receptor (CAR) T-cell studies due to the associated levels of neurotoxicity. In this study, we described five patients with chemorefractory B-cell CNS lymphoma who received CAR19 and CAR22 T-cell “Cock...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Li, Tongjuan, Zhao, Lei, Zhang, Yuanyuan, Xiao, Yi, Wang, Di, Huang, Liang, Ma, Liya, Chen, Liting, Liu, Songya, Long, Xiaolu, Meng, Fankai, Zhu, Xiaojian, Wei, Jia, Xu, Bin, Zhou, Jianfeng, Zhou, Xiaoxi
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7438944/
https://ncbi.nlm.nih.gov/pubmed/32903866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01306
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