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CRISPR and transposon in vivo screens for cancer drivers and therapeutic targets
Human cancers harbor substantial genetic, epigenetic, and transcriptional changes, only some of which drive oncogenesis at certain times during cancer evolution. Identifying the cancer-driver alterations amongst the vast swathes of “passenger” changes still remains a major challenge. Transposon and...
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| Publicat a: | Genome Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7437018/ https://ncbi.nlm.nih.gov/pubmed/32811551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02118-9 |
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