(19)F NMR‐Based Fragment Screening for 14 Different Biologically Active RNAs and 10 DNA and Protein Counter‐Screens

We report here the nuclear magnetic resonance (19)F screening of 14 RNA targets with different secondary and tertiary structure to systematically assess the druggability of RNAs. Our RNA targets include representative bacterial riboswitches that naturally bind with nanomolar affinity and high specif...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Binas, Oliver, de Jesus, Vanessa, Landgraf, Tom, Völklein, Albrecht Eduard, Martins, Jason, Hymon, Daniel, Kaur Bains, Jasleen, Berg, Hannes, Biedenbänder, Thomas, Fürtig, Boris, Lakshmi Gande, Santosh, Niesteruk, Anna, Oxenfarth, Andreas, Shahin Qureshi, Nusrat, Schamber, Tatjana, Schnieders, Robbin, Tröster, Alix, Wacker, Anna, Wirmer‐Bartoschek, Julia, Wirtz Martin, Maria Alexandra, Stirnal, Elke, Azzaoui, Kamal, Richter, Christian, Sreeramulu, Sridhar, José Blommers, Marcel Jules, Schwalbe, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Full Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7436455/
https://ncbi.nlm.nih.gov/pubmed/32794266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000476
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados