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New insights on PI3K/AKT pathway alterations and clinical outcomes in breast cancer
PI3K/AKT signaling pathway plays an important role in tumorigenesis and regulates critical cellular functions including survival, proliferation and metabolism. PIK3CA mutations and AKT activation by phosphorylation (pAKT) are often detected in many cancers and especially at high frequencies in breas...
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| Опубликовано в: : | Cancer Treat Rev |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7436195/ https://ncbi.nlm.nih.gov/pubmed/26995633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2016.03.004 |
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