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Benzylideneacetophenone Derivative Alleviates Arthritic Symptoms via Modulation of the MAPK Signaling Pathway

The benzylideneacetophenone derivative 3-(4-hydroxy-3-methoxy-phenyl)-1-{3-[1]-phenyl}-propenone (JC3 dimer) was synthesized through the dimerization of JC3. To investigate the inhibitory effects of JC3 dimer, the carrageenan/kaolin (C/K)-induced knee arthritis rat model was used in vivo and rheumat...

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Pubblicato in:Molecules
Autori principali: Sur, Bongjun, Kim, Mijin, Villa, Thea, Oh, Seikwan
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435446/
https://ncbi.nlm.nih.gov/pubmed/32707885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25153319
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