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ENaC regulation by phospholipids and DGK explained through mathematical modeling

Cystic fibrosis is a condition caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). It is also thought to increase the activity of epithelial sodium channels (ENaC). The altered function of these ion channels is one of the causes of the thick dehydrated mucus that c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Olivença, Daniel V., Voit, Eberhard O., Pinto, Francisco R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435262/
https://ncbi.nlm.nih.gov/pubmed/32811866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70630-w
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