Divergent effects of glutathione depletion on isocitrate dehydrogenase 1 and the pentose phosphate pathway in hamster liver

The liver regenerates NADPH via multiple pathways to maintain redox balance and reductive biosynthesis. The pentose phosphate pathway (PPP) contributes to hepatic lipogenesis by supplying NADPH, and it is thought to play a major role in response to oxidative stress. This study determined the signifi...

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Bibliographic Details
Published in:Physiol Rep
Main Authors: Jin, Eunsook S., Lee, Min H., Malloy, Craig R.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435027/
https://ncbi.nlm.nih.gov/pubmed/32812387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14554
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