Gene expression and regulatory factors of the mechanistic target of rapamycin (mTOR) complex 1 predict mammalian longevity

Species longevity varies significantly across animal species, but the underlying molecular mechanisms remain poorly understood. Recent studies and omics approaches suggest that phenotypic traits of longevity could converge in the mammalian target of rapamycin (mTOR) signalling pathway. The present s...

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Veröffentlicht in:GeroScience
Hauptverfasser: Mota-Martorell, Natalia, Jove, Mariona, Pradas, Irene, Berdún, Rebeca, Sanchez, Isabel, Naudi, Alba, Gari, Eloi, Barja, Gustavo, Pamplona, Reinald
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434991/
https://ncbi.nlm.nih.gov/pubmed/32578071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00210-3
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