MICAL2 is essential for myogenic lineage commitment

Contractile myofiber units are mainly composed of thick myosin and thin actin (F-actin) filaments. F-Actin interacts with Microtubule Associated Monooxygenase, Calponin And LIM Domain Containing 2 (MICAL2). Indeed, MICAL2 modifies actin subunits and promotes actin filament turnover by severing them...

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Publicat a:Cell Death Dis
Autors principals: Giarratana, Nefele, Conti, Filippo, La Rovere, Rita, Gijsbers, Rik, Carai, Paolo, Duelen, Robin, Vervliet, Tim, Bultynck, Geert, Ronzoni, Flavio, Piciotti, Roberto, Costamagna, Domiziana, Fulle, Stefania, Barravecchia, Ivana, Angeloni, Debora, Torrente, Yvan, Sampaolesi, Maurilio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434877/
https://ncbi.nlm.nih.gov/pubmed/32811811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02886-z
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