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Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen

INTRODUCTION: Observational studies estimating severe outcomes for paracetamol versus ibuprofen use have acknowledged the specific challenge of channeling bias. A previous study relying on negative controls suggested that using large-scale propensity score (LSPS) matching may mitigate bias better th...

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Detalhes bibliográficos
Publicado no:Drug Saf
Main Authors: Weinstein, Rachel B., Ryan, Patrick B., Berlin, Jesse A., Schuemie, Martijn J., Swerdel, Joel, Fife, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434801/
https://ncbi.nlm.nih.gov/pubmed/32500272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-020-00950-3
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