Host dysbiosis negatively impacts IL-9-producing T-cell differentiation and antitumour immunity

BACKGROUND: Host–microbiota interactions shape T-cell differentiation and promote tumour immunity. Although IL-9-producing T cells have been described as potent antitumour effectors, their role in microbiota-mediated tumour control remains unclear. METHODS: We analysed the impact of the intestinal m...

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Udgivet i:Br J Cancer
Main Authors: Almeida, Rafael Ribeiro, Vieira, Raquel de Souza, Castoldi, Angela, Terra, Fernanda Fernandes, Melo, Amanda Campelo L., Canesso, Maria Cecília Campos, Lemos, Luísa, Cipelli, Marcella, Rana, Nisha, Hiyane, Meire Ioshie, Pearce, Erika L., Martins, Flaviano dos Santos, Faria, Ana Maria Caetano de, Câmara, Niels Olsen Saraiva
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434765/
https://ncbi.nlm.nih.gov/pubmed/32499569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0915-6
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