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A rare case of NIPT discrepancy caused by the placental mosaicism of three different karyotypes, 47,XXX, 47,XX,+21, and 48,XXX,+21

BACKGROUND: Placental mosaicism is one of the major reasons for noninvasive prenatal testing (NIPT) discrepancy. Herein, we discovered a rare case of placenta with complex karyotypes that caused false‐positive and false‐negative results in noninvasive prenatal testing. METHODS: Next‐generation seque...

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Dettagli Bibliografici
Pubblicato in:Mol Genet Genomic Med
Autori principali: Li, Jin, Xie, Mingshui, Wang, Fang, Ma, Jianhong, Li, Jiafu, Chen, Chen, Li, Zhimin, Wang, Juan, Zhang, Yuanzhen, Li, Yirong
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434741/
https://ncbi.nlm.nih.gov/pubmed/32463164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1279
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