Doxorubicin and Edelfosine Combo-Loaded Lipid–Polymer Hybrid Nanoparticles for Synergistic Anticancer Effect Against Drug-Resistant Osteosarcoma

INTRODUCTION: The failure of chemotherapy in osteosarcoma results in drug resistance and acute side effects in the body. METHODS: In this study, we have prepared a novel folate receptor-targeted doxorubicin (DOX) and edelfosine (EDL)-loaded lipid–polymer hybrid nanoparticle (DE-FPLN) to enhance the...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Main Authors: Yang, Ping, Zhang, Lian, Wang, Tian, Liu, Qi, Wang, Jing, Wang, Yaling, Tu, Zhiquan, Lin, Feng
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2020
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7434523/
https://ncbi.nlm.nih.gov/pubmed/32884291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S259428
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