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Could imiquimod (Aldara 5% cream) or other TLR7 agonists be used in the treatment of COVID-19?
Toll-like receptor 7 is critical in recognition of single strand RNA viruses, including SARS CoV-2, and generation of anti-viral immunity. Coronaviruses evolved strategies to dampen the host immunity. Herein, we discuss the potential use of TLR7 agonists in the early stages of COVID-19 treatment.
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| Publicado no: | Med Hypotheses |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Ltd.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7434307/ https://ncbi.nlm.nih.gov/pubmed/33254510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mehy.2020.110202 |
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