The role of miRNA-155 in the immunopathogenesis of obliterative airway disease in mice induced by circulating exosomes from human lung transplant recipients with chronic lung allograft dysfunction

Human lung transplant recipients undergoing rejection induce circulatory exosomes with lung self-antigens (SAgs), K-alpha 1 Tubulin and Collagen V, and immunization of C57BL/6 mice with exosomes induced obliterative airway disease (HEI-OAD). We analyzed whether exosomes with SAgs induced immunity in...

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Опубликовано в: :Cell Immunol
Главные авторы: Bansal, Sandhya, Itabashi, Yoshihiro, Perincheri, Sudhir, Poulson, Christin, Bharat, Ankit, Smith, Michael A., Bremner, Ross M., Mohanakumar, T.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7433931/
https://ncbi.nlm.nih.gov/pubmed/32707293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2020.104172
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